講座題目:Mathematical modeling and dynamical analysis of anti-tumor drug dose-response
講座專家:鄒秀芬(武漢大學(xué)教授/博士生導(dǎo)師)
講座對象:學(xué)院教師、碩士生、本科生
講座時間:2021年5月28日 下午
講座地點:數(shù)學(xué)與統(tǒng)計學(xué)院3401
內(nèi)容摘要:In various anti-tumor drug treatment, it has become more significant within toxicological evaluation and risk assessment practices as well as have numerous biomedical applications. In this talk, we present a data-based mathematical model and dynamical analysis to quantitatively investigate dose-response of antitumor drugs and reveal critical threshold of antibody dose. The data-based modeling and quantitative simulations provide suggestions for the selection of appropriate drug dosage in the clinical treatment of cancer.
專家簡介:鄒秀芬, 武漢大學(xué)數(shù)學(xué)與統(tǒng)計學(xué)院二級教授,博士生導(dǎo)師,中國工業(yè)與應(yīng)用數(shù)學(xué)學(xué)會數(shù)學(xué)生命科學(xué)專業(yè)委員會副主任,中國運籌學(xué)會計算系統(tǒng)生物學(xué)常務(wù)理事,長期從事數(shù)學(xué)與生物醫(yī)學(xué)等交叉學(xué)科研究。近年來主持承擔(dān)了國家自然科學(xué)基金重點項目、面上項目和科技部國家重大研究計劃課題等科研課題。在癌癥等復(fù)雜疾病的海量數(shù)據(jù)集成、多尺度建模和復(fù)雜疾病的優(yōu)化控制等方面取得了一系列成果,已在“PNAS”,“SIAM on Applied Mathematics”, “Applied Mathematical Modeling”, “PLOS Computational Biology”, “Bulletin of Mathematical Biology”, “IEEE Transactions on Biomedical Engineering”等國際重要學(xué)術(shù)期刊上發(fā)表六十余篇相關(guān)的SCI學(xué)術(shù)論文。